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Glycosylation is one of the common post-translational modifications. The carbohydrate attaches the amino acid residues at the nitrogen atom of Asparagine for N-Glycosylation and the oxygen atom of Serine and Threonine for O-linked glycosylation. When immunoglobulin V-genes contain Asparagine resides in the CDRs, an N glycosylation motif may be formed during selection, of which approximately 20% of antibodies are glycosylated in the variable regions. https://www.creative-biolabs.com/N-O-Glycosylation.htm
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