Nauka i natura

In nature, there are 20 kinds of natural amino acids. In recent years, many efforts have been made in the modification of amino acids, and many non-natural amino acids have been created. Non-natural amino acids play an important role in the field of proteins and peptides. BOC-amino acid is a common and typical non-natural amino acid. There are many ways to synthesize BOC-amino acids. For example, tert-butyl oxycarbonyl (BOC) amino acids are commonly used as intermediates in the synthesis of polypeptides. The preparation method is the reaction of 1,1,3,3-tetramethylguanidinium salts of some amino acids with tert-butyloxycarbonyl azide in 4-dimethylaminopyridine as the solvent. boc amino acids
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