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Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that is then purified from the horse's serum to produce a usable product that can be used for immunosuppression. Atgam https://www.creativebiomart.net/therapeutic-proteins/p/107/equine-anti-thymocyte-globulin/
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